Protein Details: Potassium channel subfamily K member 13

Protein ID

ICDB_Pro_1482

Protein Name

Potassium channel subfamily K member 13

Gene Name

Kcnk13

Organism

Rattus norvegicus (Rat)

Length

405 amino acids

AlphaFoldDB

AF-Q9ERS0-F1-model_v4.pdb

Function

Potassium channel displaying weak inward rectification in symmetrical K(+) solution.

Sequence

MAGRGCSCSPGHLNEDNARFLLLAGLILLYLLGGAAVFSALELAQELQAKQRWEERLANFSRGHNLSREELRGFLRHYEEATKAGIRMDSVRPRWDFTGAFYFVGTVVTTIGFGMTTPATTGGKVFLIFYGLIGCASTILFFNLFLERLITVIAYVMRTCHHQQLRRRGTVARDNRKAPRKGEADSLAGWKPSVYYVMLILCLASVAISCGASALYTTMEGWSYFDSVYFCFVASSTIGFGDLVSSQNAQYENEGLYRFVNFFFILMGVCCIYSMFNVISILIKQTVNWILRKLDSGCFPQCQRGLLRSRRNVVMPGNIRNRCNISIETDGVMESDTDGRRLSGEMISMKDTNKVSLAILQKQLSEMANGGPHQTSTSSRDDEFSGGVGAFAVMNNRLAETSGDR

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Ubiquitous. In brain expression is rather low and restricted to the olfactory bulb and tubercle; to the ventromedial hypothalamic nucleus; lateral septal nucleus dorsal; lateral mammillary nucleus; lateral parabrachial nuclei; reticular nucleus and reunions nuclei.

DOI ID

10.1074/jbc.m008985200

RefSeq

NP_071629.1